jetMESSENGER®

jetMESSENGER-1-1-435x242

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Specifications

Reagent	jetMESSENGER^®
Molecule delivered	mRNA
Applications	Gene expression Genome Editing Stem cell differentiation Reprogramming Immunotherapy
Cell types	Hard-to-transfect cells Adherent and suspension cells Primary cells (Neurons, Stem cells, Immune cells, fibroblasts, …) Post-mitotic cells
Number of transfections	1.5 ml of jetMESSENGER^® transfection reagent is sufficient to perform up to 1500 transfections in 24-well plates or 375 transfections in 6-well plates
Storage	Store jetMESSENGER^® at 5 °C ± 3°C. Expiry date is indicated in the certificate of analysis (available in "My account") and on the product.
Provided with	mRNA buffer

jetMESSENGER® is a highly efficient and gentle mRNA transfection reagent. mRNA transfection presents many advantages versus DNA transfection:

no risk of genome integration, hence no genome modification of the transfected cell
no promoter regulation issue
no need to reach the nucleus for efficient expression
more gentle process
Allows higher gene expression than main competitors on a variety of cell lines

jetMESSENGER® is extremely efficient especially in hard-to-transfect cells compared to other mRNA transfection reagents. Transfection with jetMESSENGER® leads to outstanding mRNA delivery in a wide variety of cell lines, such as neurons, primary cells, stem cells and various cancer cell lines,
Suitable for different applications

jetMESSENGER® is designed for several applications, such as gene expression, CRISPR/Cas-9 gene editing, reprogramming experiments in fibroblasts and stem cells, and immunotherapy assays.
Extremely gentle on cells

By eliminating the need to reach the nucleus for efficient expression, jetMESSENGER® allows transfection of quiescent and slow dividing cells. In addition, jetMESSENGER® operates through an extremely gentle process. Cell viability remains extremely high during transfection and cell morphology is maintained.